Benepure Pharmaceutical Co., Ltd.

1. The utilization of TRP(tryptophan) in patients with depression was observed in the experiment of antidepressant effect, and it was found that the L-TRP utilization in patients with major depression was significantly lower than that in patients with minor depression.

2. Central analgesic effect TRP may play a central analgesic effect by increasing the central content of 5-hydroxytryptamine (5-HT). However, after the descending 5-HT fibers reach the spinal cord, they can activate enkephalin neurons in the posterior glial region through the mediation of interneurons, which can inhibit the transmission of peripheral pain information to secondary neurons in a presynaptic inhibition way, thus playing a central analgesic role.

3. Effects of cardiovascular system on different hypertensive animal models in rats. The results show that TRP also has antihypertensive activity. 4. Hypnotic effects 5-hydroxytryptophan in the body can use vitamin B6 to produce the precursor of the neurohormone serotonin, which promotes sleep and mental stability.

5. Anti-stress physiological effects Studies have found that injections of 5-hydroxytryptophan can reduce the amount of mice that attack and kill each other for a short period of time, in proportion to the amount of 5-hydroxytryptophan.

6. Effects on neuroendocrine activities 5-hydroxytryptophan can be converted into some hormones directly involved in endocrine activities, but also can be converted into central neurotransmitter 5-hydroxytryptophan indirectly affect the release of neurohormones. 7. Suppress your appetite